Verifying Sarcoidosis Activity: Chitotriosidase Versus ACE in Sarcoidosis – A Case-Control Study

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Verifying Sarcoidosis Activity: Chitotriosidase versus ACE in Sarcoidosis – a Case-control Study

BACKGROUND Until now, a proper biomarker(s) to evaluate sarcoidosis activity has not been recognized. The aims of this study were to evaluate the sensitivity and specificity of the two biomarkers of sarcoidosis activity already in use (serum angiotensin converting enzyme - ACE and serum chitotriosidase) in a population of 430 sarcoidosis patients. The activities of these markers were also analy...

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Bronchoalveolar lavage chitotriosidase activity as a biomarker of sarcoidosis.

BACKGROUND Chitotriosidase (CTO) was shown to be a good biomarker of sarcoidosis. Increased levels in bronchoalveolar lavage fluid (BALF) were reported and associated with more severe forms of the disease. OBJECTIVES The aim of the study was to evaluate the value of CTO in BALF as a routine biomarker of sarcoidosis. METHODS The study included 85 patients in 9 control subjects in whom serum ...

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Chitotriosidase activity in sarcoidosis and some other pulmonary diseases.

BACKGROUND Patients with sarcoidosis have elevated levels of several markers of inflammation. Particularly high levels have been reported for chitotriosidase. In this study, we evaluate whether determining chitotriosidase in serum would be useful in the diagnosis and clinical management of patients with sarcoidosis. METHODS Patients with newly diagnosed sarcoidosis and patients with asthma, f...

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Sarcoidosis following Tattoo: A case report

Between 20% and 35% of patients with systemic sarcoidosis have skin lesions. One of the unusual cutaneous presentations of sarcoidosis is a granulomatous tattoo reaction that may present alone or with other features of sarcoidosis. We present a case of sarcoidosis whom presented with multiple nodules on tattood skin accompanied with facial pulsy, parotid enlargement and uveitis.

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Polymorphic cutaneous sarcoidosis: A case report

Sarcoidosis (Besnier-Boeck-Schaumann disease) is a multisystem disease of unknown etiology with various cutaneous presentations. It is characterized by the presence of non-caseating ‘naked’ granulomas in the affected tissue. We report a case of polymorphic cutaneous sarcoid in a 39-year-old immunocompetent male. He was visited at our outpatient department with multiple asymptomatic red colored ...

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ژورنال

عنوان ژورنال: Journal of Medical Biochemistry

سال: 2016

ISSN: 1452-8266

DOI: 10.1515/jomb-2016-0017